When it pays to rush: interpreting morphogen gradients prior to steady-state
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چکیده
منابع مشابه
When it pays to rush: interpreting morphogen gradients prior to steady-state.
During development, morphogen gradients precisely determine the position of gene expression boundaries despite the inevitable presence of fluctuations. Recent experiments suggest that some morphogen gradients may be interpreted prior to reaching steady-state. Theoretical work has predicted that such systems will be more robust to embryo-to-embryo fluctuations. By analyzing two experimentally mo...
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In this paper we establish the existence of positive solutions to a system of steady-state Neumann boundary problems. This system has been observed in some biological experiments, morphogen gradients; effects of Decapentaplegic (Dpp) and short gastrulation (Sog). Mathematical difficulties arise from this system being nonquasimonotone and semilinear. We overcome such difficulties by using the fi...
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This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and thendistribute the resultingwork under the sameorsimilar license to thisone. Thework must be attributed back to the original author and commercial use is not permitted without specif...
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متن کاملReply to "Comment on 'Dynamically maintained steady-state pressure gradients' "
A reply is made to Duncan's Comment [T. L. Duncan, Phys. Rev. E 61, 4661 (2000)] on my earlier paper [D. P. Sheehan, Phys. Rev. E 57, 6660 (1998)] in which he raises an apparent second-law paradox arising from dynamically maintained, steady-state pressure gradients. Resolutions to this paradox are considered in light of current theoretical and experimental understanding.
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2009
ISSN: 1478-3975
DOI: 10.1088/1478-3975/6/4/046020